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Pain and Analgesic related insomnia

Published:December 19, 2022DOI:https://doi.org/10.1016/j.pmn.2022.11.002

      Abstract

      Objectives

      The aim of this review is to describe the effects of analgesics on sleep.

      Data sources

      Systematic search of the databases of PubMed and the Cochrane Library was performed between January and September 2021.

      Review/Analysis methods

      The search included all articles on the topic published during the past 20 years (2000-2020). The search strategy was developed using a controlled vocabulary of known studies meeting the inclusion criteria and focused on the following terms: chronic pain, pain, sleep disturbance, insomnia, analgesic, analgesic medication, antidepressants, antiepileptic drugs, nonsteroidal drugs, opioids, and quality of life. Two reviewers independently considered the studies for inclusion in the review, assessed the risk of bias, and extracted data.

      Design

      Review and analysis.

      Results

      A total of 37 studies met the inclusion criteria: 15 analyzed the effects of opioids, 6 those of nonsteroidal anti-inflammatory drugs and acetaminophen, and 16 the effects of adjuvant analgesics.

      Conclusions

      Sleep quality may be adversely affected by a variety of medications used in clinical practice, including those used in analgesic indications. The class of analgesics most affecting sleep quality are opioids.
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      References

        • Alford D.
        • German J.
        • Samet J.
        • Cheng D.
        • Lloyd-Travaglini C.
        • Saitz R.
        Primary care patients with drug use report chronic pain and self-medicate with alcohol and other drugs.
        Journal of General Internal Medicine. 2016; 31: 486-491
      1. Al-Obaid, A. M., & Mian, M. S. (1993). Tenoxicam. Analytical Profiles of Drug Substances and Excipients, 431...459. doi:10.1016/s0099-5428(08)60248-8.

        • Alrashood S.
        Carbamazepine.
        Chapter Three - Carbamazepine, Profiles of Drug Substances, Excipients and Related Methodology. 41. Elsevier, Academic Press, Amsterdam, Netherlands2016: 133-321https://doi.org/10.1016/bs.podrm.2015.11.001 (Elsevier)
        • American Academy of Sleep Medicine
        International classification of sleep disorders.
        3rd ed. American Academy of Sleep Medicine, Darien, IL2014
        • Askay S.
        • Bombardier C.
        • Patterson D.
        Effect of acute and chronic alcohol abuse on pain management in a trauma center.
        Expert Review of Neurotherapeutics. 2014; 9: 271-277
        • Ayoub S.
        Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action.
        Temperature (Austin, Tex.). 2021; 8: 351-371
        • Babul N.
        • Noveck R.
        • Chipman H.
        • Roth S.
        • Gana T.
        • Albert K.
        Efficacy and safety of extended-release, once-daily tramadol in chronic pain: A randomized 12-week clinical trial in osteoarthritis of the knee.
        Journal of Pain and Symptom Management. 2004; 28: 59-71
        • Backonja M.
        • Glanzman R.
        Gabapentin dosing for neuropathic pain: Evidence from randomized, placebo-controlled clinical trials.
        Clinical Therapeutics. 2003; 25: 81-104
        • Baker S.
        • McBeth J.
        • Chew-Graham C.
        • Wilkie R.
        Musculoskeletal pain and co-morbid insomnia in adults: A population study of the prevalence and impact on restricted social participation.
        BMC Family Practice. 2017; 18: 17
        • Baldassarri S.
        • Beitel M.
        • Zinchuk A.
        • Redeker N.
        • Oberleitner D.
        • Oberleitner L.
        • Carrasco D.
        • Madden L.
        • Lipkind N.
        • Fiellin D.
        • Bastian L.
        • Chen K.
        • Yaggi H.
        • Barry D.
        Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment.
        Sleep and Breathing. 2020; 24: 1729-1737
        • Becker N.
        • Thomsen A.
        • Olsen A.
        • Sjøgren P.
        • Bech P.
        • Eriksen J.
        Pain epidemiology and health related quality of life in chronic non-malignant pain patients referred to a Danish multidisciplinary pain center.
        Pain. 1997; 73: 393-400
        • Belhomme N.
        • Doudnikoff C.
        • Polard E.
        • Henriot B.
        • Isly H.
        • Jego P.
        Aspirine: Indications et utilisation durant la grossesse.
        La Revue de Médecine Interne. 2017; 38: 825-832
        • Benca R.
        Sleep and psychiatric disorders.
        Archives of General Psychiatry. 1992; : 49
        • Brick N.
        Carbamazepine for acute and chronic pain in adults.
        Clinical Journal of Oncology Nursing. 2011; 15: 335-336
        • Brown R.
        • Basheer R.
        • McKenna J.
        • Strecker R.
        • McCarley R.
        Control of sleep and wakefulness.
        Physiological Reviews. 2012; 92: 1087-1187
        • Caldwell J.
        • Hale M.
        • Boyd R.
        • Hague J.
        • Iwan T.
        • Shi M.
        • Lacouture P.
        Treatment of osteoarthritis pain with controlled release oxycodone or fixed combination oxycodone plus acetaminophen added to nonsteroidal antiinflammatory drugs: A double blind, randomized, multicenter, placebo controlled trial.
        J Rheumatol. 1999; 264: 862-869
        • Carette S.
        • Oakson G.
        • Guimont C.
        • Steriade M.
        Sleep electroencephalography and the clinical response to amitriptyline in patients with fibromyalgia.
        Arthritis & Rheumatism. 1995; 38: 1211-1217
        • Chalon S.
        • Pereira A.
        • Lainey E.
        • Vandenhende F.
        • Watkin J.
        • Staner L.
        • Granier L.
        Comparative effects of duloxetine and desipramine on sleep EEG in healthy subjects.
        Psychopharmacology. 2005; 177: 357-365
        • Chan L.
        • Anderson G.
        Pharmacokinetic and pharmacodynamic drug interactions with ethanol (alcohol).
        Clinical Pharmacokinetics. 2014; 53: 1115-1136
        • Cheatle M.
        • Foster S.
        • Pinkett A.
        • Lesneski M.
        • Qu D.
        • Dhingra L.
        Assessing and managing sleep disturbance in patients with chronic pain.
        Anesthesiology Clinics. 2016; 34: 379-393
        • Condén E.
        • Rosenblad A.
        Insomnia predicts long-term all-cause mortality after acute myocardial infarction: A prospective cohort study.
        International Journal of Cardiology. 2016; 215: 217-222
        • de Haas S.
        • Otte A.
        • de Weerd A.
        • van Erp G.
        • Cohen A.
        • van Gerven J.
        Exploratory polysomnographic evaluation of pregabalin on sleep disturbance in patients with epilepsy.
        Journal of Clinical Sleep Medicine. 2007; 3: 473-478
        • de Martino M.
        • Chiarugi A.
        • Boner A.
        • Montini G.
        • de’ Angelis G.
        Working towards an appropriate use of ibuprofen in children: An evidence-based appraisal.
        Drugs. 2017; 77: 1295-1311
        • Deatherage J.
        • Roden R.
        • Zouhary K.
        Normal sleep architecture.
        Seminars in Orthodontics. 2009; 15: 86-87
        • Dimsdale J.
        • Norman D.
        • DeJardin D.
        • Wallace M.
        The effect of opioids on sleep architecture.
        Journal of Clinical Sleep Medicine. 2007; 3: 33-36
        • Dufour M.
        • Archer L.
        • Gordis E.
        Alcohol and the elderly.
        Clinics In Geriatric Medicine. 1992; 8: 127-141
        • Edinger J.
        • Arnedt J.
        • Bertisch S.
        • Carney C.
        • Harrington J.
        • Lichstein K.
        • Sateia M.
        • Troxel W.
        • Zhou E.
        • Kazmi U.
        • Heald J.
        • Martin J.
        Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline.
        Journal of Clinical Sleep Medicine. 2021; 17: 255-262
        • Elvir-Lazo O.
        • White P.
        The role of multimodal analgesia in pain management after ambulatory surgery.
        Current Opinion in Anaesthesiology. 2010; 23: 697-703
        • Florete O.
        • Xiang J.
        • Vorsanger G.
        Effects of extended-release tramadol on pain-related sleep parameters in patients with osteoarthritis.
        Expert Opinion on Pharmacotherapy. 2008; 9: 1817-1827
        • Flower R.
        • Vane J.
        Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol).
        Nature. 1972; 240: 410-411
        • Foldvary-Schaefer N.
        • De Leon Sanchez I.
        • Karafa M.
        • Mascha E.
        • Dinner D.
        • Morris H.
        Gabapentin increases slow-wave sleep in normal adults.
        Epilepsia. 2002; 43: 1493-1497
        • Frohnhofen H.
        Pain and sleep.
        Zeitschrift für Gerontologie und Geriatrie. 2018; 51: 871-874
        • Furey S.
        • Hull S.
        • Leibowitz M.
        • Jayawardena S.
        • Roth T.
        A randomized, double-blind, placebo-controlled, multicenter, 28-day, polysomnographic study of gabapentin in transient insomnia induced by sleep phase advance.
        Journal of Clinical Sleep Medicine. 2014; 10: 1101-1109
        • Garbarino S.
        • Lanteri P.
        • Bragazzi N.
        • Magnavita N.
        • Scoditti E.
        Role of sleep deprivation in immune-related disease risk and outcomes.
        Communications Biology. 2021; 4
        • Garner B.
        • Hopkinson S.
        • Ketz A.
        • Landis C.
        • Trego L.
        Auricular acupuncture for chronic pain and insomnia: A randomized clinical trial.
        Medical Acupuncture. 2018; 30: 262-272
        • Gauthier E.
        • Guzick S.
        • Brummett C.
        • Baghdoyan H.
        • Lydic R.
        Buprenorphine disrupts sleep and decreases adenosine concentrations in sleep-regulating brain regions of Sprague Dawley rat.
        Anesthesiology. 2011; 115: 743-753
        • Gengo F.
        Effects of ibuprofen on sleep quality as measured using polysomnography and subjective measures in healthy adults.
        Clinical Therapeutics. 2006; 28: 1820-1826
        • Gigli G.
        • Placidi F.
        • Diomedi M.
        • Maschio M.
        • Silvestri G.
        • Scalise A.
        • Marciani M.
        Nocturnal sleep and daytime somnolence in untreated patients with temporal lobe epilepsy: Changes after treatment with controlled-release carbamazepine.
        Epilepsia. 1997; 38: 696-701
        • Gillin J.
        • Wyatt R.
        • Fram D.
        • Snyder F.
        The relationship between changes in REM sleep and clinical improvement in depressed patients treated with amitriptyline.
        Psychopharmacology. 1978; 59: 267-272
        • Gimbel J.
        • Richards P.
        • Portenoy R.
        Controlled-release oxycodone for pain in diabetic neuropathy: A randomized controlled trial.
        Neurology. 2003; 60: 927-934
        • Gresham S.
        • Webb W.
        • Williams R.
        Alcohol and caffeine: Effect on inferred visual dreaming.
        Science. 1963; 140: 1226-1227
        • Guion K.
        • Avis K.
        Sleep Architecture.
        in: Goldstein S. Naglieri J. Encyclopedia of Child Behavior and Development. Springer US, New York City2011: 1372-1374
        • Gutstein H.
        • Akil H.
        Goodman and Gilman's the pharmacological basis of therapeutics.
        10th ed. McGraw-Hill, New York City2001
        • Haack M.
        • Simpson N.
        • Sethna N.
        • Kaur S.
        • Mullington J.
        Sleep deficiency and chronic pain: potential underlying mechanisms and clinical implications.
        Neuropsychopharmacology. 2020; 45: 205-216
        • Hayes W.
        • Lemon M.
        • Farver D.
        Gabapentin enacarbil for treatment of restless legs syndrome in adults.
        Annals of Pharmacotherapy. 2012; 46: 229-239
        • Hester J.
        • Tang N.
        Insomnia co-occurring with chronic pain: Clinical features, interaction, assessments and possible interventions.
        Reviews in Pain. 2008; 2: 2-7
        • Holsboer-Trachsler E.
        • Prieto R.
        Effects of pregabalin on sleep in generalized anxiety disorder.
        International Journal of Neuropsychopharmacology. 2013; 16: 925-936
        • Horne J.
        Aspirin and nonfebrile waking oral temperature in healthy men and women: Links with SWS changes?.
        Sleep. 1989; 12: 516-521
        • Horne J.
        • Percival J.
        • Traynor J.
        Aspirin and human sleep.
        Electroencephalography and Clinical Neurophysiology. 1980; 49: 409-413
        • Hutka P.
        • Krivosova M.
        • Muchova Z.
        • Tonhajzerova I.
        • Hamrakova A.
        • Mlyncekova Z.
        • Mokry J.
        • Ondrejka I.
        Association of sleep architecture and physiology with depressive disorder and antidepressants treatment.
        International Journal of Molecular Sciences. 2021; 22: 1333
        • Iacovides S.
        • Avidon I.
        • Bentley A.
        • Baker F.
        Diclofenac potassium restores objective and subjective measures of sleep quality in women with primary dysmenorrhea.
        Sleep. 2009; 32: 1019-1026
        • Irish L.
        • Kline C.
        • Gunn H.
        • Buysse D.
        • Hall M.
        The role of sleep hygiene in promoting public health: A review of empirical evidence.
        Sleep Medicine Reviews. 2015; 22: 23-36
        • Jank R.
        • Gallee A.
        • Boeckle M.
        • Fiegl S.
        • Pieh C.
        Chronic pain and sleep disorders in primary care.
        Pain Research and Treatment. 2017; 2017: 1-9
        • Johnson E.
        • Roehrs T.
        • Roth T.
        • Breslau N.
        Epidemiology of alcohol and medication as aids to sleep in early adulthood.
        Sleep. 1998; 21: 178-186
        • Jung A.
        • Staiger T.
        • Sullivan M.
        The efficacy of selective serotonin reuptake inhibitors for the management of chronic pain.
        Journal of General Internal Medicine. 1997; 12: 384-389
        • Kantor T.
        Use of diclofenac in analgesia.
        The American Journal of Medicine. 1986; 80: 64-69
        • Kato H.
        • Miyazaki M.
        • Takeuchi M.
        • Tsukuura H.
        • Sugishita M.
        • Noda Y.
        • Yamada K.
        A retrospective study to identify risk factors for somnolence and dizziness in patients treated with pregabalin.
        Journal of Pharmaceutical Health Care and Sciences. 2015; 1: 22
        • Kay D.
        Human sleep during chronic morphine intoxication.
        Psychopharmacologia. 1975; 44: 117-124
        • Kluge M.
        • Schüssler P.
        • Steiger A.
        Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression.
        European Neuropsychopharmacology. 2007; 17: 527-531
        • Knutson K.
        Sleep and pain: Summary of the 2015 Sleep in America Poll.
        Sleep Health. 2015; 1: 85
        • Kosinski M.
        • Janagap C.
        • Gajria K.
        • Schein J.
        • Freedman J.
        Pain relief and pain-related sleep disturbance with extended-release tramadol in patients with osteoarthritis.
        Current Medical Research and Opinion. 2007; 23: 1615-1626
        • Kress H.
        Clinical update on the pharmacology, efficacy and safety of transdermal buprenorphine.
        European Journal of Pain. 2009; 13: 219-230
        • Lavie P.
        • Nahir M.
        • Lorber M.
        • Scharf Y.
        Nonsteroidal antiinflammatory drug therapy in rheumatoid arthritis patients. Lack of association between clinical improvement and effects on sleep.
        Arthritis & Rheumatism. 1991; 34: 655-659
        • Lee Y.
        • Chen P.
        A review of SSRIs and SNRIs in neuropathic pain.
        Expert Opinion on Pharmacotherapy. 2010; 11: 2813-2825
        • Li M.
        • Zhang X.
        • Hou W.
        • Tang Z.
        Insomnia and risk of cardiovascular disease: A meta-analysis of cohort studies.
        International Journal of Cardiology. 2014; 176: 1044-1047
        • Liu G.
        • Karim M.
        • Xu L.
        • Wang S.
        • Yang C.
        • Ding L.
        • Wang Y.
        Efficacy and tolerability of gabapentin in adults with sleep disturbance in medical illness: A systematic review and meta-analysis.
        Frontiers in Neurology. 2017; 8: 316
        • Lo H.
        • Yang C.
        • Lo H.
        • Lee C.
        • Ting H.
        • Tzang B.
        Treatment effects of gabapentin for primary insomnia.
        Clinical Neuropharmacology. 2010; 33: 84-90
        • Marshansky S.
        • Mayer P.
        • Rizzo D.
        • Baltzan M.
        • Denis R.
        • Lavigne G.
        Sleep, chronic pain, and opioid risk for apnea.
        Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2018; 87: 234-244
        • Mathias J.
        • Cant M.
        • Burke A.
        Sleep disturbances and sleep disorders in adults living with chronic pain: A meta-analysis.
        Sleep Medicine. 2018; 52: 198-210
        • McCrae C.
        • Lichstein K.
        Secondary insomnia: Diagnostic challenges and intervention opportunities.
        Sleep Medicine Reviews. 2001; 5: 47-61
        • Medic G.
        • Wille M.
        • Hemels M.
        Short- and long-term health consequences of sleep disruption.
        Nature and Science of Sleep. 2017; 9: 151-161
        • Meerlo P.
        • Sgoifo A.
        • Suchecki D.
        Restricted and disrupted sleep: Effects on autonomic function, neuroendocrine stress systems and stress responsivity.
        Sleep Medicine Reviews. 2008; 12: 197-210
        • Menassé R.
        • Hedwall P.
        • Kraetz J.
        • Pericin C.
        • Riesterer L.
        • Sallmann A.
        • Ziel R.
        • Jaques R.
        Pharmacological properties of diclofenac sodium and its metabolites.
        Scandinavian Journal of Rheumatology. 2009; 7: 5-16
        • Mercadante S.
        • Girelli D.
        • Casuccio A.
        Sleep disorders in advanced cancer patients: prevalence and factors associated.
        Supportive Care in Cancer. 2004; 12: 355-359
        • Mogri M.
        • Desai H.
        • Webster L.
        • Grant B.
        • Mador M.
        Hypoxemia in patients on chronic opiate therapy with and without sleep apnea.
        Sleep and Breathing. 2009; 13: 49-57
        • Moore R.
        • Derry S.
        • Aldington D.
        • Cole P.
        • Wiffen P.
        Amitriptyline for neuropathic pain in adults.
        Cochrane Database of Systematic Reviews. 2015; 2015CD008242
        • Murphy P.
        • Badia P.
        • Myers B.
        • Boecker M.
        • Wright K.
        Nonsteroidal anti-inflammatory drugs affect normal sleep patterns in humans.
        Physiology & Behavior. 1994; 55: 1063-1066
        • Naito K.
        • Osama H.
        • Ueno R.
        • Hayaishi O.
        • Honda K.
        • Inoué S.
        Suppression of sleep by prostaglandin synthesis inhibitors in unrestrained rats.
        Brain Research. 1988; 453: 329-336
        • Nelson A.
        • Battersby A.
        • Baghdoyan H.
        • Lydic R.
        Opioid-induced decreases in rat brain adenosine levels are reversed by inhibiting adenosine deaminase.
        Anesthesiology. 2009; 111: 1327-1333
        • Nicholson A.
        • Watson G.
        • Derry S.
        • Wiffen P.
        Methadone for cancer pain.
        Cochrane Database of Systematic Reviews. 2017; 2CD003971
        • Nicholson B.
        Gabapentin use in neuropathic pain syndromes.
        Acta Neurologica Scandinavica. 2000; 101: 359-371
        • Ohayon M.
        Relationship between chronic painful physical condition and insomnia.
        Journal of Psychiatric Research. 2005; 39: 151-159
        • Oishi Y.
        • Yoshida K.
        • Scammell T.
        • Urade Y.
        • Lazarus M.
        • Saper C.
        The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.
        Brain, Behavior, and Immunity. 2015; 47: 172-177
        • Onen S.
        • Onen F.
        • Courpron P.
        • Dubray C.
        How pain and analgesics disturb sleep.
        The Clinical Journal of Pain. 2005; 21: 422-431
        • Ott G.
        • Rao U.
        • Lin K.
        • Gertsik L.
        • Poland R.
        Effect of treatment with bupropion on EEG sleep: relationship to antidepressant response.
        The International Journal of Neuropsychopharmacology. 1999; 7: 275-281
        • Placidi F.
        • Diomedi M.
        • Scalise A.
        Effect of anticonvulsants on nocturnal sleep in epilepsy.
        Neurology. 2000; 5451: S25-S32
      2. Portenoy, R., Mehta, Z., & Ahmed, E. (2021). Prevention and management of side effects in patients receiving opioids for chronic pain. UpToDate. Retrieved August 15, 2021 from https://www-uptodate-com.ezproxy.is.cuni.cz/contents/prevention-and-management-of-side-effects-in-patients-receiving-opioids-for-chronic-pain/contributors.

        • Ramesh V.
        • Nair D.
        • Zhang S.
        • Hakim F.
        • Kaushal N.
        • Kayali F.
        • Wang Y.
        • Li R.
        • Carreras A.
        • Gozal D.
        Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway.
        Journal of Neuroinflammation. 2012; 9: 91
        • Riemann D.
        • Baglioni C.
        • Bassetti C.
        • Bjorvatn B.
        • Dolenc Groselj L.
        • Ellis J.
        • Espie C.
        • Garcia-Borreguero D.
        • Gjerstad M.
        • Gonçalves M.
        • Hertenstein E.
        • Jansson-Fröjmark M.
        • Jennum P.
        • Leger D.
        • Nissen C.
        • Parrino L.
        • Paunio T.
        • Pevernagie D.
        • Verbraecken J.
        • et al.
        European guideline for the diagnosis and treatment of insomnia.
        Journal of Sleep Research. 2017; 26: 675-700
        • Riemann D.
        • Gann H.
        • Hohagen F.
        • Bahro M.
        • Müller W.
        • Bergef M.
        The effect of carbamazepine on endocrine and sleep EEG variables in a patient with 48-hour rapid cycling, and healthy controls.
        Neuropsychobiology. 2004; 27: 163-170
        • Robertson J.
        • Purple R.
        • Cole P.
        • Zaiwalla Z.
        • Wulff K.
        • Pattinson K.
        Sleep disturbance in patients taking opioid medication for chronic back pain.
        Anaesthesia. 2016; 71: 1296-1307
      3. Roehrs, T., & Roth, T. The effects of medications on sleep quality and sleep architecture. UpToDate. Retrieved March 15, 2021 from https://www-uptodate.com.ezproxy.is.cuni.cz/contents/the-effects-of-medications-on-sleep-quality-and-sleep-architecture.

        • Rokyta R.
        Fyziologie a patologická fyziologie: Pro klinickou praxi (1. vydání). Praha.
        Grada Publishing, Hlavni mesto Praha, Czech Republic2015
        • Rosen I.
        • Aurora R.
        • Kirsch D.
        • Carden K.
        • Malhotra R.
        • Ramar K.
        • Abbasi-Feinberg F.
        • Kristo D.
        • Martin J.
        • Olson E.
        • Rosen C.
        • Rowley J.
        • Shelgikar A.
        Chronic opioid therapy and sleep: An American Academy of Sleep Medicine position statement.
        Journal of Clinical Sleep Medicine. 2019; 15: 1671-1673
        • Roth T.
        • Arnold L.
        • Garcia-Borreguero D.
        • Resnick M.
        • Clair A.
        A review of the effects of pregabalin on sleep disturbance across multiple clinical conditions.
        Sleep Medicine Reviews. 2014; 18: 261-271
        • Roth T.
        • Lankford D.
        • Bhadra P.
        • Whalen E.
        • Resnick E.
        Effect of pregabalin on sleep in patients with fibromyalgia and sleep maintenance disturbance: A randomized, placebo-controlled, 2-way crossover polysomnography study.
        Arthritis Care & Research. 2012; 64: 597-606
        • Sagawa Y.
        • Kondo H.
        • Matsubuchi N.
        • Takemura T.
        • Kanayama H.
        • Kaneko Y.
        • Kanbayashi T.
        • Hishikawa Y.
        • Shimizu T.
        Alcohol has a dose-related effect on parasympathetic nerve activity during sleep.
        Alcoholism: Clinical and Experimental Research. 2011; 35: 2093-2100
        • Sateia M.
        International classification of sleep disorders.
        Chest. 2014; 146: 1387-1394
        • Scott L.
        • Perry C.
        Tramadol.
        Drugs. 2000; 60: 139-176
        • Semenchuk M.
        • Sherman S.
        • Davis B.
        Double-blind, randomized trial of bupropion SR for the treatment of neuropathic pain.
        Neurology. 2001; 57: 1583-1588
        • Serdarevic M.
        • Osborne V.
        • Striley C.
        • Cottler L.
        The association between insomnia and prescription opioid use: Results from a community sample in Northeast Florida.
        Sleep Health. 2017; 3: 368-372
        • Shaw I.
        • Lavigne G.
        • Mayer P.
        • Choinière M.
        Acute intravenous administration of morphine perturbs sleep architecture in healthy pain-free young adults: A preliminary study.
        Sleep. 2005; 28: 677-682
        • Shin S.
        • Lee H.
        • Kim Y.
        • Choi Y.
        • Kim S.
        • Kwon H.
        • Oh S.
        • Kang J.
        • Sohn C.
        • Lee S.
        • Baek J.
        • Min Y.
        • Kim C.
        • Chung J.
        Clinical usefulness of hydromorphone-OROS in improving sleep disturbances in Korean cancer patients: A multicenter, prospective, open-label study.
        Cancer Research and Treatment. 2014; 46: 331-338
        • Schramm P.
        • Poland R.
        • Rao U.
        Bupropion response on sleep quality in patients with depression: Implications for increased cardiovascular disease risk.
        European Neuropsychopharmacology. 2014; 24: 207-214
        • Schutte-Rodin S.
        • Broch L.
        • Buysse D.
        • Dorsey C.
        • Sateia M.
        Clinical guideline for the evaluation and management of chronic insomnia in adults.
        Journal of Clinical Sleep Medicine. 2008; 4: 487-504
        • Siegel J.
        Sleep viewed as a state of adaptive inactivity.
        Nature Reviews Neuroscience. 2009; 10: 747-753
        • Simon G.
        • VonKorff M.
        Prevalence, burden, and treatment of insomnia in primary care.
        American Journal of Psychiatry. 1997; 154: 1417-1423
        • Sofi F.
        • Cesari F.
        • Casini A.
        • Macchi C.
        • Abbate R.
        • Gensini G.
        Insomnia and risk of cardiovascular disease: A meta-analysis.
        European Journal of Preventive Cardiology. 2012; 21: 57-64
        • Sondergaard K.
        • Gislason G.
        NSAIDs and cardiac arrest.
        European Heart Journal. 2017; 38: 1788-1789
        • Surrall K.
        • Smith J.
        • Bird H.
        • Okala B.
        • Othman H.
        • Padwick D.
        Effect of ibuprofen and indomethacin on human plasma melatonin.
        Journal of Pharmacy and Pharmacology. 1987; 39: 840-843
        • Tang H.
        • Vitiello M.
        • Perlis M.
        • Mao J.
        • Riegel B.
        A pilot study of audio–visual stimulation as a self-care treatment for insomnia in adults with insomnia and chronic pain.
        Applied Psychophysiology and Biofeedback. 2014; 39: 219-225
        • Tang N.
        • Wright K.
        • Salkovskis P.
        Prevalence and correlates of clinical insomnia co-occurring with chronic back pain.
        Journal of Sleep Research. 2007; 16: 85-95
        • Tasali E.
        • Leproult R.
        • Ehrmann D.
        • Van Cauter E.
        Slow-wave sleep and the risk of type 2 diabetes in humans.
        Proceedings of the National Academy of Sciences. 2008; 105: 1044-1049
        • Thakkar M.
        • Sharma R.
        • Sahota P.
        Alcohol disrupts sleep homeostasis.
        Alcohol. 2015; 49: 299-310
        • Tripathi R.
        • Rao R.
        • Dhawan A.
        • Jain R.
        • Sinha S.
        Opioids and sleep: A review of literature.
        Sleep Medicine. 2020; 67: 269-275
        • Urits I.
        • Peck J.
        • Orhurhu M.
        • Wolf J.
        • Patel R.
        • Orhurhu V.
        • Kaye A.
        • Viswanath O.
        Off-label antidepressant use for treatment and management of chronic pain: Evolving understanding and comprehensive review.
        Current Pain and Headache Reports. 2019; 23: 66
        • Uthman B.
        • Bazil C.
        • Beydoun A.
        • Schulze-Bonhage A.
        • Benabou R.
        • Whalen E.
        • Emir B.
        • Griesing T.
        • Leon T.
        Long-term add-on pregabalin treatment in patients with partial-onset epilepsy: Pooled analysis of open-label clinical trials.
        Epilepsia. 2010; 51: 968-978
        • van de Glind E.
        • Hooft L.
        • Tulner L.
        • Tulen J.
        • te Water W.
        • Kuper I.
        • Hamburger H.
        • de Rooij S.
        • van Munster B.
        Acetaminophen for self-reported sleep problems in an elderly population (ASLEEP): A randomized double-blind placebo-controlled trial.
        International Journal of Geriatric Psychiatry. 2016; 31: 955-957
        • Van Erum J.
        • Van Dam D.
        • Sheorajpanday R.
        • De Deyn P.
        Sleep architecture changes in the APP23 mouse model manifest at onset of cognitive deficits.
        Behavioural Brain Research. 2019; 373112089
        • Van Gastel A.
        Drug-induced insomnia and excessive sleepiness.
        Sleep Medicine Clinics. 2018; 13: 147-159
        • Vena C.
        • Parker K.
        • Cunningham M.
        • Clark J.
        • McMillan S.
        Sleep-wake disturbances in people with cancer part I: An overview of sleep, sleep regulation, and effects of disease and treatment.
        Oncology Nursing Forum. 2004; 31: 735-746
        • Walder B.
        • Tramer M.
        • Blois R.
        The effects of two single doses of tramadol on sleep: a randomized, cross-over trial in healthy volunteers.
        European Journal of Anaesthesiology. 2001; 18: 36-42
        • Walker J.
        • Farney R.
        • Rhondeau S.
        Chronic opioid use is a risk factor for the development of central sleep apnea and ataxic breathing.
        J Clin Sleep Med. 2007; 35: 455-461
        • Webster L.
        • Smith M.
        • Mackin S.
        • Iverson M.
        Comparative effects of morning vs evening dosing of extended-release hydromorphone on sleep physiology in patients with low back pain: A pilot study.
        Pain Medicine. 2015; 16: 460-471
        • Wickwire E.
        • Shaya F.
        • Scharf S.
        Health economics of insomnia treatments: The return on investment for a good night's sleep.
        Sleep Medicine Reviews. 2016; 30: 72-82
        • Wilson L.
        • Dorosz L.
        Possible role of the opioid peptides in sleep.
        Medical Hypotheses. 1984; 14: 269-280
        • Wilson S.
        • Argyropoulos S.
        Antidepressants and sleep.
        Drugs. 2005; 65: 927-947
        • Wolff R.
        • Clar C.
        • Lerch C.
        • Kleijnen J.
        Epidemiologie von nicht tumorbedingten chronischen Schmerzen in Deutschland.
        Der Schmerz. 2011; 25: 26-44
        • Xiao L.
        • Tang Y.
        • Smith A.
        • Xiang Y.
        • Sheng L.
        • Chi Y.
        • Du W.
        • Guo S.
        • Jiang Z.
        • Zhang G.
        • Luo X.
        Nocturnal sleep architecture disturbances in early methadone treatment patients.
        Psychiatry Research. 2010; 179: 91-95
        • Yang J.
        • Elphick M.
        • Sharpley A.
        • Cowen P.
        Effects of carbamazepine on sleep in healthy volunteers.
        Biological Psychiatry. 1989; 26: 324-328
        • Yarlas A.
        • Miller K.
        • Wen W.
        • Lynch S.
        • Ripa S.
        • Pergolizzi J.
        • Raffa R.
        Buprenorphine transdermal system improves sleep quality and reduces sleep disturbance in patients with moderate-to-severe chronic low back pain: Results from two randomized controlled trials.
        Pain Practice. 2016; 16: 345-358