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Multimodal Pain Management of Children Diagnosed with Osteogenesis Imperfecta: An Integrative Literature Review

Published:October 04, 2022DOI:https://doi.org/10.1016/j.pmn.2022.08.014

      Abstract

      Objectives

      The objective of this literature review was to evaluate multimodal therapies and interventions that help prevent progression and manage pain in children with OI.

      Design

      A systematic review of literature utilizing PRISMA guidelines.

      Data sources

      The Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete, PubMed, PsycINFO, UpToDate, and ProQuest Nursing & Allied Health Source.

      Review/Analysis methods

      Existing literature on pain management in pediatric patients diagnosed with OI was reviewed and appraised. Fifteen studies met the criteria for review.

      Results

      Results indicated that therapies addressing pain management are most effective when they use a multimodal approach that promotes bone strength, psychological support, reduces the risk of fractures, increases bone stability, and maintains physiological function. Four multimodal treatments for pain management in children with OI were identified including bisphosphonate therapy, surgical intervention, physical therapy, and psychosocial support.

      Conclusions

      Developing a finite understanding of the utilization of multimodal therapies to manage and treat pain can assist in engineering treatments that improve the quality of life for children diagnosed with OI.
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