Abstract
Aims
Psychosocial and sensory factors, including anxiety, depression, and pressure pain
threshold have been used to cluster chronic symptoms in irritable bowel syndrome (IBS).
This study examined the contribution of psychosocial sensory factors on pain interference
and quality of life (QOL) in this population.
Design
We performed a cross-sectional analysis of baseline data from a randomized controlled
trial.
Settings
Two gastrointestinal clinics, general communities, and two large campuses of a public
university in the Northeastern United States.
Participants/Subjects
Eighty young adults with IBS aged 21 ± 2.57 years (76.25% female).
Methods
Demographic and psychosocial factors including anxiety, depression, fatigue, cognition
or general concerns, sleep disturbance, self-efficacy, coping, and food intake were
measured as independent variables. Quantitative sensory testing was conducted to measure
mechanical, thermal, and pressure pain thresholds. Self-reported pain measured by
the brief pain inventory (BPI) and IBS-QOL were assessed as the outcome variables.
Regression analysis and mediation analysis were conducted to determine the associated
factors of IBS pain and QOL.
Results
Age, sex, and psychosocial factors including coping, self-efficacy, alcohol intake,
mechanical pain sensitivity, and cold pain threshold were significantly associated
with pain interference (all p < 0.05). Coping, and self-efficacy were significantly
associated with IBS-QOL (all p < 0.05). In the mediation analysis, coping catastrophizing
and self-efficacy were indirectly associated with IBS-QOL mediated by fatigue.
Conclusions
Psychosocial factors including coping and self-efficacy, and quantitative sensory
testing factors significantly correlate with self-reported pain and QOL among young
adults with IBS. This preliminary research calls for further interventional studies
that target personalized psychosocial and quantitative sensory factors to improve
pain management and quality of life in IBS patients.
Keywords
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Article info
Publication history
Published online: January 21, 2022
Accepted:
December 24,
2021
Received in revised form:
November 16,
2021
Received:
July 19,
2021
Footnotes
☆This study was supported by the National Institute of Nursing Research of the National Institutes of Health (NIH-NINR) under award number: NIH-NINR P20NR016605 (PI Starkweather; Pilot PI: Cong). Jie Chen received research support from Virginia Stone Fund through American Nurses Foundations Research Grants Award, Eastern Nursing Research Society (ENRS)/Council for the Advancement of Nursing Science Dissertation Award, Sigma Theta Tau International Mu Chapter Research Award, and the University of Connecticut Dissertation Fellowship.
Identification
Copyright
© 2021 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.
