Pain Management Nursing
Volume 10, Issue 1 , Pages 3-13 , March 2009

Pharmacologic Management of Sleep Disturbances in Noncancer-Related Pain

  • Christine Miaskowski, RN, PhD, FAAN

      Affiliations

    • Corresponding Author InformationAddress correspondence to: Christine Miaskowski, RN, PhD, FAAN, Professor and Associate Dean for Academic Affairs, Department of Physiological Nursing, University of California, 2 Koret Way—Box 0610, San Francisco, CA 94143-0610

Received 9 October 2007 ,Revised 23 April 2008 ,Accepted 16 May 2008.

References 

  1. Anch M, Browman CP, Mitler MM, Walsh J. Sleep: A scientific perspective. Englewood, NJ: Prentice Hall; 1988;
  2. Anonymous. Myths and facts about long-acting opioids in chronic pain: A multidisciplinary analysis. ONS News / Oncology Nursing Society. 2004;19(9 Suppl):55–56
  3. Anonymous. Tramadol—Biovail Corporation. Drugs in R & D. 2004;5(3):182–183
  4. Atkinson JH, Slater MA, Patterson TL, Grant I, Garfin SR. Prevalence, onset, and risk of psychiatric disorders in men with chronic low back pain: a controlled study. Pain. 1991;45(2):111–121
  5. Avinza. Avinza (morphine sulfate extended-release capsules). [package insert] Bristol, TN: King Pharmaceuticals; 2006;
  6. Babul N, Noveck R, Chipman H, Roth SH, Gana T, Albert K. Efficacy and safety of extended-release, once-daily tramadol in chronic pain: A randomized 12-week clinical trial in osteoarthritis of the knee. Journal of Pain and Symptom Management. 2004;28(1):59–71
  7. Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Research. 1989;28(2):193–213
  8. Caldwell JR. Comparison of the efficacy, safety, and pharmacokinetic profiles of extended-release ketoprofen and piroxicam in patients with rheumatoid arthritis. Clinical Therapeutics. 1994;16(2):222–235
  9. Caldwell JR, Hale ME, Boyd RE, Hague JM, Iwan T, Shi M, et al. Treatment of osteoarthritis pain with controlled release oxycodone or fixed combination oxycodone plus acetaminophen added to nonsteroidal antiinflammatory drugs: A double blind, randomized, multicenter, placebo controlled trial. The Journal of Rheumatology. 1999;26(4):862–869
  10. Caldwell JR, Rapoport RJ, Davis JC, Offenberg HL, Marker HW, Roth SH, et al. Efficacy and safety of a once-daily morphine formulation in chronic, moderate-to-severe osteoarthritis pain: Results from a randomized, placebo-controlled, double-blind trial and an open-label extension trial. Journal Pain and Symptom Management. 2002;23(4):278–291
  11. Cohen MJM, Menefee LA, Doghramji K, Anderson WR, Frank ED. Sleep in chronic pain: Problems and treatments. International Review of Psychiatry (Abingdon, England). 2000;12(2):115–126
  12. Collett BJ. Chronic opioid therapy for noncancer pain. British Journal of Anaesthesia. 2001;87(1):133–143
  13. Deardorff W. Breaking the cycle of chronic pain and insomnia. http://www.spine-health.com/topics/conserv/insomnia/insomnia1.html2005;Accessed February 21, 2007
  14. Devi V, Shankar PK. Ramelteon: A melatonin receptor agonist for the treatment of insomnia. Journal of Postgraduate Medicine. 2008;54(1):45–48
  15. Drewes AM. Pain and sleep disturbances with special reference to fibromyalgia and rheumatoid arthritis. Rheumatology (Oxford, England). 1999;38(11):1035–1038
  16. Drewes AM, Arendt-Nielsen L. Pain and sleep in medical diseases: interactions and treatment possibilities (A review). Sleep Research Online. 2001;4(2):67–76
  17. Ebert B, Wafford KA, Deacon S. Treating insomnia: Current and investigational pharmacological approaches. Pharmacology & Therapeutics. 2006;112(3):612–629
  18. Elliott TE, Renier CM, Palcher JA. Chronic pain, depression, and quality of life: Correlations and predictive value of the SF-36. Pain Medicine (Malden, Mass.). 2003;4(4):331–339
  19. Farney RJ, Walker JM, Cloward TV, Rhondeau S. Sleep-disordered breathing associated with long-term opioid therapy. Chest. 2003;123(2):632–639
  20. Gana TJ, Pascual MLG, Fleming RRB, Schein JR, Janagap CC, Xiang J, et al. Extended-release tramadol in the treatment of osteoarthritis: A multicenter, randomized, double-blind, placebo-controlled clinical trial. Current Medical Research and Opinion. 2006;22(7):1391–1401
  21. Hair PI, Curran MP, Keam SJ. Tramadol extended-release tablets. Drugs. 2006;66(15):2017–2027
  22. Hardo PG, Kennedy TD. Night sedation and arthritic pain. Journal of the Royal Society of Medicine. 1991;84(2):73–75
  23. Hardo PG, Wasti SA, Tennant A. Night pain in arthritis: Patients at risk from prescribed night sedation. Annals of the Rheumatic Diseases. 1992;51(8):972–973
  24. Hays RD, Martin SA, Sesti AM, Spritzer KL. Psychometric properties of the Medical Outcomes Study Sleep measure. Sleep Medicine. 2005;6(1):41–44
  25. Janagap C, Schein J, Kosinski M, Vorsanger G. Extended-release tramadol improves sleep in osteoarthritis. Orlando, Florida: Poster presented at the 17th annual clinical meeting of the American Academy of Pain Management; September 7-10, 2006; 2006;
  26. Jordan JM, Bernard SL, Callahan LF, Kincade JE, Konrad TR, DeFriese GH. Self-reported arthritis-related disruptions in sleep and daily life and the use of medical, complementary, and self-care strategies for arthritis: the National Survey of Self-Care and Aging. Archives of Family Medicine. 2000;9(2):143–149
  27. Kay DC, Pickworth WB, Neidert GL, Falcone D, Fishman PM, Othmer E. Opioid effects on computer-derived sleep and EEG parameters in nondependent human addicts. Sleep. 1979;2(2):175–191
  28. King SA, Strain JJ. Benzodiazepine use by chronic pain patients. The Clinical Journal of Pain. 1990;6(2):143–147
  29. Kivitz A, Ma C, Ahdieh H, Galer BS. A 2-week, multicenter, randomized, double-blind, placebo-controlled, dose-ranging, phase III trial comparing the efficacy of oxymorphone extended release and placebo in adults with pain associated with osteoarthritis of the hip or knee. Clinical Therapeutics. 2006;28(3):352–364
  30. Kosinski M, Janagap C, Gajria K, Schein J, Freedman J. Pain relief and pain-related sleep disturbance with extended-release tramadol in patients with osteoarthritis. Current Medical Research and Opinion. 2007;23:1615–1626
  31. Kundermann B, Spernal J, Huber MT, Krieg JC, Lautenbacher S. Sleep deprivation affects thermal pain thresholds but not somatosensory thresholds in healthy volunteers. Psychosomatic Medicine. 2004;66(6):932–937
  32. Lee KA, Gay CL. Sleep in late pregnancy predicts length of labor and type of delivery. American Journal of Obstetrics and Gynecology. 2004;191(6):2041–2046
  33. Leigh TJ, Bird HA, Hindmarch I, Wright V. A comparison of sleep in rheumatic and nonrheumatic patients. Clinical and Experimental Rheumatology. 1987;5(4):363–365
  34. Leigh TJ, Hindmarch I, Bird HA, Wright V. Comparison of sleep in osteoarthritic patients and age and sex matched healthy controls. Annals of the Rheumatic Diseases. 1988;47(1):40–42
  35. Markenson JA, Croft J, Zhang PG, Richards P. Treatment of persistent pain associated with osteoarthritis with controlled-release oxycodone tablets in a randomized controlled clinical trial. The Clinical Journal of Pain. 2005;21(6):524–535
  36. Matsumoto AK, Babul N, Ahdieh H. Oxymorphone extended-release tablets relieve moderate to severe pain and improve physical function in osteoarthritis: results of a randomized, double-blind, placebo- and active-controlled phase III trial. Pain Medicine (Malden, Mass.). 2005;6(5):357–366
  37. Menefee LA, Cohen MJ, Anderson WR, Doghramji K, Frank ED, Lee H. Sleep disturbance and nonmalignant chronic pain: A comprehensive review of the literature. Pain Medicine (Malden, Mass.). 2000;1(2):156–172
  38. Murphy PJ, Badia P, Myers BL, Boecker MR, Wright KP. Nonsteroidal antiinflammatory drugs affect normal sleep patterns in humans. Physiology & Behavior. 1994;55(6):1063–1066
  39. Nicholson B. Responsible prescribing of opioids for the management of chronic pain. Drugs. 2003;63(1):17–32
  40. Opana ER. Opana ER (oxymorphone hydrochloride) extended-release tablets. [package insert] Chadds Ford, PA: Endo Pharmaceuticals; 2006;
  41. Otis JD, Keane TM, Kerns RD. An examination of the relationship between chronic pain and post-traumatic stress disorder. Journal of Rehabilitation Research and Development. 2003;40(5):397–405
  42. Oxycontin. Oxycontin (oxycodone HCl controlled-release) tablets. [package insert] Stamford, CT: Purdue Pharma; 2005;
  43. Pain Prevention Rehabilitation Center. Sleep medications. http://painprevention.net/sleep_aids.aspx2008;
  44. Peloso PM, Bellamy N, Bensen W, Thomson GT, Harsanyi Z, Babul N, et al. Double blind randomized placebo control trial of controlled release codeine in the treatment of osteoarthritis of the hip or knee. The Journal of Rheumatology. 2000;27(3):764–771
  45. Peter D. Hart Research Associates. Americans talk about pain (A survey among adults nationwide conducted for Research America). http://www.researchamerica.org/polldata/2003/painpoll03.pdfRetrieved November 28, 2007
  46. Raffa RB, Nayak RK, Liao S, Minn FL. The mechanism(s) of action and pharmacokinetics of tramadol hydrochloride. Reviews in Contemporary Pharmacotherapy. 1995;6:485–497
  47. Ricci JA, Stewart WF, Chee E, Leotta C, Foley K, Hochberg MC. Pain exacerbation as a major source of lost productive time in US workers with arthritis. Arthritis and Rheumatism. 2005;53(5):673–681
  48. Romano JM, Turner JA. Chronic pain and depression: Does the evidence support a relationship?. Psychological Bulletin. 1985;97(1):18–34
  49. Roth SH, Fleischmann RM, Burch FX, Dietz F, Bockow B, Rapoport RJ, et al. Around-the-clock, controlled-release oxycodone therapy for osteoarthritis-related pain: Placebo-controlled trial and long-term evaluation. Archives of Internal Medicine. 2000;160(6):853–860
  50. Shaw IR, Lavigne G, Mayer P, Choiniere M. Acute intravenous administration of morphine perturbs sleep architecture in healthy pain-free young adults: A preliminary study. Sleep. 2005;28(6):677–682
  51. Snyder-Halpern R, Verran JA. Instrumentation to describe subjective sleep characteristics in healthy subjects. Research in Nursing & Health. 1987;10(3):155–163
  52. Tan G, Jensen MP, Thornby JI, Shanti BF. Validation of the Brief Pain Inventory for chronic nonmalignant pain. The Journal of Pain: Official Journal of the American Pain Society. 2004;5(2):133–137
  53. Ultram ER. Ultram ER (tramadol HCl) extended-release tablets. [package insert] Raritan, NJ: Pricara, Ortho-McNeil; 2006;
  54. Vallerand AH. The use of long-acting opioids in chronic pain management. The Nursing Clinics of North America. 2003;38(3):435–445
  55. Wilcox S, Brenes GA, Levine D, Sevick MA, Shumaker SA, Craven T. Factors related to sleep disturbance in older adults experiencing knee pain or knee pain with radiographic evidence of knee osteoarthritis. Journal of the American Geriatrics Society. 2000;48(10):1241–1251
  56. Wisconsin Medical Society Task Force on Pain Management. Guidelines for the assessment and management of chronic pain. WMJ: Official Publication of the State Medical Society of Wisconsin. 2004;103(3):13–42
  57. Zitman FG, Linssen AC, Edelbroek PM, Stijnen T. Low dose amitriptyline in chronic pain: the gain is modest. Pain. 1990;42(1):35–42

PII: S1524-9042(08)00104-5

doi: 10.1016/j.pmn.2008.05.002

Pain Management Nursing
Volume 10, Issue 1 , Pages 3-13 , March 2009

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